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Known significant impurities in Tromethamine that can potentially cause health problems include:

2-amino-1,3-propanediol (APD)

2-amino-2-methyl-1,3-propanediol (AMPD)

2-(N-methylamino)-1,3-propanediol (MMAPD)

2-(N-methylamino)-2-hydroxymethyl-1,3-propanediol (MMTA)

2-(N,N-dimethylamino)-2-hydroxymethyl-1,3-propanediol (DMTA).

https://geoffpain.substack.com/p/relative-lethality-of-covid-19-vaccines

Lipid impurities for Moderna include Endotoxin in Cholesterol

https://geoffpain.substack.com/p/moderna-ordered-to-get-its-endotoxin

and

Lipid manufacturer published disclaimer

https://geoffpain.substack.com/p/lnps-contaminated-with-endotoxin

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I'm sure one of the impurities is endotoxin; but because this is measured AFTER formulation into LNPs, I think this has to do with the adducts, aldehydes and who knows what else.

Intermediaries, metals and elements, Tris contaminants would be measured upstream, I think.

But why is Pfizer not testing? Because they don't have to?

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