The argument among all vaccine researchers is that you can use specific epitopes from the RBD, the most immunogenic ones, while avoiding the drawbacks of using the entire, highly immunogenic RBD, which is indeed, literally toxic and causes significant immune exhaustion when used as an antigenic target.
Inserting the NTD is short to inserting the FCS, it is one of the nastiest fragments of the entire thing. So, as the kids say, lol, lmao even.
Moderna can make a boiled egg I don't want it ! They never made anything worth while in their almost 20 years of (government funded, paid by you the tax payer) existence. Do you think they will make something now? I very much doubt it.
As to pregnant women - STOP taking any vaccines or meds. If your doctor advized you to take it, find another doctor. He or she is NOT trustworthy.
Oh I am just trying to read the Pharma/FDA regulatory moves and countermoves. I see hopeful signs that Pfizer will not be around much longer and Moderna's vax severely restricted. Small steps, but important.
Somehow or another I lost track of your substack articles. My bad! Perhaps I had been waiting for some email alert, and that never happened. As always, thank you!
Pfizer, in their Australian trials, showed that the T cell response to RBD peptides is very poor, in contrast to spike peptides. I have never understood this part. To make things worse, I have also seen a study that showed that the T cell response is mostly to the ORF1, not the spike. Have been reading and writing too much, so I don't recall the reference. However, as with the schmantibodies, the T cell response has issues as well. Huge ones. Currently writing it up... It once again seems to be that so much depends on HOW it is being measured.
Can you tell me where to go to sign the petition? I’m injured from pfizer and intend never to get another shot ever again. My trust has bottomed out because they lied, didn’t acknowledge the injuries and I believe there’s big investments in this technology which clouds their ability to see clearly.
But look, they can use a lower dose!!! Gah! Thank you for this. I am still interested in the process of how BioNTech abandoned their first vaccine using the RBD, and pivoted to the spike protein. I'm sure Pfizer had something to do with it.
Still, this may explain why Moderna is hawking their new improved vaccine to ACIP despite not having the vaccine formally in the queue to be assessed by the FDA.
Bnt162b2 was reintroduced into the clinical trial the day before Pfizer responded to the Operation Warp Speed RFP. They pay royalties to the NIH to use the stabilized pre fusion spike design (as do Moderna). The rbd version was George Fu Gao’s of China CDC preferred design which BioNtech were developing for Fosun to market in China (never licensed). There was a scheme to exploit European regulatory loopholes to obtain a marketing authorisation for BioNtech (with Moderna’s virtually identically product piggy backing through) that survived the end of the WHO pandemic declaration.
BioNTech called their bnt162b1 design their leading candidate in published papers in June / July 2020 then suddenly dropped it for the NIH designed version.
I know it's like they fed parameters for the opposite of "safe and effective", into ChatGpt and then said,
"hell yeah! Lets do this!". That part of what set off my BS alarm. It's almost impossible to screw it up this badly. So then that leaves intentionality.😐😐😉
But that's called "conspiracy", and that's a dirty word😉🤣😂🤣🤦♀️
Pfizer is the sacrificial lamb on the alter of Pharma.😉
They will bear the full brunt of "Wuhan lie". And as their sacrificed, a whole bunch of evidence will disappear, and the "new" Moderna god will be worshipped, although they might change its name to a suitably "greenwashed" friendlier, but still "dedicated to modern health future", BS.
Personally, I would say yes. But I also think that the usual stock suspects (including the Pfizer CEO's, are waaaay ahead of me.
One of those two companies are going down, in less than the next 3yrs (realistically at the rate of data coming out, more like 18mths) but which one- depends on who has the bigger military contracts and tech bro fan base- which at this point is Moderna.
Moderna essentially IS DARPA child. Its more useful for Pfizer, which already has a shite rep for dogy business and practices over DECADES, to take the fall for the c19 "mistakes were made" show. Remember, apparently the platform is not "bad", its the "rush job".🤨😐🙄 #weknowbetter
They tried to "pin" the "bad vaccine" narrative on Oxford-AstraZeneca, but I think they underestimated how quickly the social media grapevine can work, when its not proactively censored/manipulated. They wont make that mistake again. Especially not with the "mis, dis, and mal" laws slid on through the last 3 yrs.😉
So, unless they magic up some other "vaccine" bogey company, that everyone took heaps of shots from.... its pflatout Pfizer.
Thank you. The platform is deadly is very well explained. I have had difficulty explaining why this transfection is so deadly to docs, let alone non-scientists. Sometimes I get through for a moment, there is a flicker of fear, then they shut down again.
There are so many topics of importance like this. They are all filled with extraordinary complexity, be it science, history, economics (and on and on). I believe the challenge we face is how to tell the tale in terms that laypeople can relate to. Not dumbed-down or over-simplified, but distilled. Details certainly matter, but too often, things are framed in ways that are over-complexified (not a word, but it should be). It’s a real and significant challenge!
The argument among all vaccine researchers is that you can use specific epitopes from the RBD, the most immunogenic ones, while avoiding the drawbacks of using the entire, highly immunogenic RBD, which is indeed, literally toxic and causes significant immune exhaustion when used as an antigenic target.
Inserting the NTD is short to inserting the FCS, it is one of the nastiest fragments of the entire thing. So, as the kids say, lol, lmao even.
Thanks JP!
Well, but they use a lower dose/sarc. And get the more antibodies, schmantibodies/sarc
Oh, and it is self-adjuvanting!/sarc. No more dsRNA needed, or endotoxin etc etc
Do you have the sequence or epitopes (precise epitopes) used in their vaccine ? My brain is still recovering from the flu lol.
Perhaps this may be helpful -> https://hiddencomplexity.substack.com/p/repeated-rbd-boosting-leads-to-immune?utm_source=publication-search
here are the references they cited. Not sure how helpful they will be
https://www.sciencedirect.com/science/article/pii/S0092867420312344
https://www.sciencedirect.com/science/article/pii/S0092867421004281
https://www.cell.com/cell-host-microbe/fulltext/S1931-3128(21)00133-5
The last one on the NTD is pretty interesting, at least for me. Hope this helps and get better fast.
and as usual you were 3!!! years ahead, lol.
Moderna can make a boiled egg I don't want it ! They never made anything worth while in their almost 20 years of (government funded, paid by you the tax payer) existence. Do you think they will make something now? I very much doubt it.
As to pregnant women - STOP taking any vaccines or meds. If your doctor advized you to take it, find another doctor. He or she is NOT trustworthy.
Oh I am just trying to read the Pharma/FDA regulatory moves and countermoves. I see hopeful signs that Pfizer will not be around much longer and Moderna's vax severely restricted. Small steps, but important.
Thank God may be some sense is finally sipping into the world !
Somehow or another I lost track of your substack articles. My bad! Perhaps I had been waiting for some email alert, and that never happened. As always, thank you!
Pfizer, in their Australian trials, showed that the T cell response to RBD peptides is very poor, in contrast to spike peptides. I have never understood this part. To make things worse, I have also seen a study that showed that the T cell response is mostly to the ORF1, not the spike. Have been reading and writing too much, so I don't recall the reference. However, as with the schmantibodies, the T cell response has issues as well. Huge ones. Currently writing it up... It once again seems to be that so much depends on HOW it is being measured.
Can you tell me where to go to sign the petition? I’m injured from pfizer and intend never to get another shot ever again. My trust has bottomed out because they lied, didn’t acknowledge the injuries and I believe there’s big investments in this technology which clouds their ability to see clearly.
Thank you!!
Try this
https://www.call2halt19.ca/
Thank you for speaking out. Sp many who were injured do not. We need you! Please keep telling your truth.
Nice work in using the two Spike subunits most associated with allergen-like properties and class switching to IgG4.
It's no coincidence, as these are highly immunogenic, and why tolerance is to be expected.
They couldn't get it more wrong.
Does SARS-CoV-2 Possess “Allergen-Like” Epitopes?
https://www.mdpi.com/2673-8112/5/4/55
But look, they can use a lower dose!!! Gah! Thank you for this. I am still interested in the process of how BioNTech abandoned their first vaccine using the RBD, and pivoted to the spike protein. I'm sure Pfizer had something to do with it.
Still, this may explain why Moderna is hawking their new improved vaccine to ACIP despite not having the vaccine formally in the queue to be assessed by the FDA.
Bnt162b2 was reintroduced into the clinical trial the day before Pfizer responded to the Operation Warp Speed RFP. They pay royalties to the NIH to use the stabilized pre fusion spike design (as do Moderna). The rbd version was George Fu Gao’s of China CDC preferred design which BioNtech were developing for Fosun to market in China (never licensed). There was a scheme to exploit European regulatory loopholes to obtain a marketing authorisation for BioNtech (with Moderna’s virtually identically product piggy backing through) that survived the end of the WHO pandemic declaration.
BioNTech called their bnt162b1 design their leading candidate in published papers in June / July 2020 then suddenly dropped it for the NIH designed version.
I know it's like they fed parameters for the opposite of "safe and effective", into ChatGpt and then said,
"hell yeah! Lets do this!". That part of what set off my BS alarm. It's almost impossible to screw it up this badly. So then that leaves intentionality.😐😐😉
But that's called "conspiracy", and that's a dirty word😉🤣😂🤣🤦♀️
Pfizer is the sacrificial lamb on the alter of Pharma.😉
They will bear the full brunt of "Wuhan lie". And as their sacrificed, a whole bunch of evidence will disappear, and the "new" Moderna god will be worshipped, although they might change its name to a suitably "greenwashed" friendlier, but still "dedicated to modern health future", BS.
🙄😐🤦♀️
#samesamenotdifferent #follownone #mistakeswereNOTmade #getlocalised
Oh I have been thinking that and documenting this very thing since 2023. I think I need to update this substack post.
https://mariagutschi.substack.com/p/pfizer-is-going-down-and-it-was-likely
Are we confident enough to short Pfi$er?
Personally, I would say yes. But I also think that the usual stock suspects (including the Pfizer CEO's, are waaaay ahead of me.
One of those two companies are going down, in less than the next 3yrs (realistically at the rate of data coming out, more like 18mths) but which one- depends on who has the bigger military contracts and tech bro fan base- which at this point is Moderna.
Moderna essentially IS DARPA child. Its more useful for Pfizer, which already has a shite rep for dogy business and practices over DECADES, to take the fall for the c19 "mistakes were made" show. Remember, apparently the platform is not "bad", its the "rush job".🤨😐🙄 #weknowbetter
They tried to "pin" the "bad vaccine" narrative on Oxford-AstraZeneca, but I think they underestimated how quickly the social media grapevine can work, when its not proactively censored/manipulated. They wont make that mistake again. Especially not with the "mis, dis, and mal" laws slid on through the last 3 yrs.😉
So, unless they magic up some other "vaccine" bogey company, that everyone took heaps of shots from.... its pflatout Pfizer.
BTJMO.
#caveat- I am not a stockbroker, pharmaceutical rep or finance expert.
Please speak to a financial expert before betting the farm on a comment from an unknown individual on Substack.
#useyourhead #follownone
thank you Maria,
i still could not see anywhere mention of increased Mucosal Immunity
.. you know, the frontier viruses must pass before entering the human body proper
Ha! It is all about antibodies schmantibodies (TM) and they don't care which kind of Ab or even if they work.
And thank you
Your jocularity is the perfect balance to this scientific insanity
“For people who are unvaccinated, more doses may be needed than are shown in this table” - to kill them.
Thank you for this. Truly awful, but not unbelievable (sadly).
I believe the Platform itself is the problem, and the target antigen is secondary.
The call to withdraw the COVID injectables is an excellent effort, but then the Platform itself must be revealed for what it is.
Offering two posts for your readers:
https://entwine.substack.com/p/the-call-to-halt-19
https://entwine.substack.com/p/the-platform-is-deadly
Thank you. The platform is deadly is very well explained. I have had difficulty explaining why this transfection is so deadly to docs, let alone non-scientists. Sometimes I get through for a moment, there is a flicker of fear, then they shut down again.
Very frustrating.
There are so many topics of importance like this. They are all filled with extraordinary complexity, be it science, history, economics (and on and on). I believe the challenge we face is how to tell the tale in terms that laypeople can relate to. Not dumbed-down or over-simplified, but distilled. Details certainly matter, but too often, things are framed in ways that are over-complexified (not a word, but it should be). It’s a real and significant challenge!
Thank you for the restack, btw :)